Arrange drumettes in a baking dish and season them with salt and pepper. Preheat your oven to 400 degrees Fahrenheit and place the drumettes in your oven when it is fully heated.
Cook the drumettes for 30 minutes and remove the baking dish from the oven. Using a colander placed over the sink, quickly drain off excess fat from the drumettes and return them to the baking dish. Slather the drumettes with barbecue sauce, using the kitchen brush, and return the pan to the oven.
Bake the drumettes for 15 more minutes and remove the dish from the oven. Test internal temperature of a large drumette using an instant-read kitchen thermometer to ensure it reaches 165 F.